Former genetic engineer now speaks out against GMO risks

By Ken Roseboro
Published: May 31, 2013

Category: GM Food Labeling and Regulation

Thierry Vrain former GE scientist

Thierry Vrain is a former scientist with Agriculture Canada

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The “conversion” of former anti-GMO activist Mark Lynas to GMO promoter has garnered huge media attention, but Thierry Vrain, Ph.D., a former genetic engineer who speaks out against the risks of genetically engineered foods, has far more credibility—and a far more important story to tell the public.

Thierry Vrain’s career has spanned the full range of agriculture—from being a proponent of “chemical” agriculture and genetic engineering to being an advocate for organic farming and an opponent of GMOs.

A native of France, Vrain earned an undergraduate degree in plant physiology from the Université de Caen and a doctoral degree from North Carolina State University. After moving to Canada he taught plant physiology at Université du Québec in Montréal. Then he worked for 30 years as a research scientist for the Canadian government in Québec and British Columbia where he conducted research on genetically modified potatoes, among other projects. He was director of the biotechnology department at the Pacific Agri-Food Research Centre in Summerland, BC.

After 35 years of research and teaching of soil and molecular biology, Vrain retired to a small farm in Courtenay, BC called Innisfree. Today, Thierry Vrain is a gardener, a teacher, and a passionate speaker about organic gardening—from soil health to GMOs.



Tell me a little more about your background.

Thierry Vrain: I worked in three research institutes in Montreal, Vancouver, and Summerland. I was the head of a research group using molecular biology tools. We worked on food crops. I was genetically engineering small fruit and potatoes for nematode resistance using the snowdrop lectin gene.

The genetically engineered apple (now under regulatory review in the US and Canada) originated in our group though I wasn’t involved with the research.


Did you speak publically in favor of genetic engineering when you were at Agriculture Canada?  

Vrain: Yes, I just took it on as my job. I explained the safety of the technology to the public and did a good amount of lecturing, educating small groups.


What led you to change from a supporter of genetically modified foods to an opponent?

Vrain: I have some difficulties with how the controversy is handled. If you aren’t a scientist you don’t understand the science. If you are a scientist and discover things that are of concern, then you are accused of doing “pseudoscience” and often viciously attacked by the industry and academics on the payroll. This has happened many times, for example to Arpad Pusztai in England and then Ignacio Chapela, who discovered GMO contamination in native corn in Mexico. He was attacked and almost fired from his post at the University of California. A year later his findings were confirmed.

There are now quite a number of research publications, in peer reviewed journals, showing concerns from feeding GM corn and soy to rats. Those studies are ignored and shouldn’t be. Federal agencies should repeat the studies and must test these crops for safety.

Research scientists from the US Food & Drug Administration made it clear in the early 1990s that there could be indirect effects from eating GM crops, such as toxins, allergens, and nutritional deficiencies. Those warnings were ignored. Now a good number of publications are confirming the predictions of the FDA scientists.

It troubles me that money and the bottom line are at the root of the use of the technology.


You say that the science behind genetic engineering is based on a misunderstanding. Please elaborate on this.

Vrain: When we started with genetic engineering in the 1980s, the science was based on the theory that one gene produces one protein. But we now know, since the human genome project, that a gene can create more than one protein. The insertion of genes in the genome through genetic engineering interrupts the coding sequence of the DNA, creating truncated, rogue proteins, which can cause unintended effects. It’s an invasive technology.

Biotech companies ignore these rogue proteins; they say they are background noise. But we should pay attention to them. It must be verified that they produce no negative effects.

A key point is that the concern about genetic engineering should be about the proteins. Many plants and animals are not edible because their proteins are toxic or poisonous. To test for the safety of Bt crops, scientists have mostly fed the pure protein to rats, and there may be no problem. But it’s different if you feed rats the whole GM plant because they are getting these rogue proteins that could cause harm.

How do you explain published papers describing how rats and mice suffer organ damage from eating GM corn or soy? It’s too easy to dismiss those as pseudoscience. Rats and mice are the canary in the mine, and we should be paying attention to what happens to them.


Why don’t more people recognize the misunderstanding behind genetic engineering?

Vrain: The human genome project is only 10 years old. How long did it take for people to recognize that the earth is not flat?


And there are many scientists that promote genetic engineering of foods.

Vrain: There are a lot of people on the payroll and a lot of grant money flowing from biotech companies to academia. I used to be employed by Agriculture Canada. I did my job, and didn’t question things too much.


What are some of the other risks you see with GMOs?

Vrain: When I hear we need genetic engineering to feed the world, I cringe. It turns out that there is no increase in yield, no decrease use of pesticides, and the process is of highly questioned safety.

Even if genetic engineering was perfectly safe, I still question it because of genetic pollution. Organic crops and foods are becoming contaminated.

I’m also concerned about contamination of the environment with antibiotic resistant genes. Every GM crop has these genes. The preliminary evidence we have is that bacteria in the soil and in the human gut are capable of picking those genes up. Considering the alarm I hear from medical people about losing antibiotics, I think this should be a serious concern.


What about the GMO apple that may be commercialized?

Vrain: There’s no research or toxicity tests to show that it’s not toxic.

I question whether it’s useful. It’s not different from what other biotech companies do, which is to put out a product and make money.

Apple growers, conventional and organic, are very concerned that people will reject their products if a GM apple is introduced.

The apple is a symbol of health. An engineered apple does not have the same health appeal, and the industry knows that.


What led you to favor organic agriculture?

Vrain: I used to be a soil biologist and focused on fertilizers and pesticides. When I retired I started to look around and, quite frankly, the organic side of soil biology made more sense than what I had taught.

Industrial agriculture relies on inputs that are good for the chemical industry. Unfortunately, we have evidence that inputs are degrading soil biodiversity. Industrial agriculture completely ignores the ecology of the soil.

When I was a soil biologist I would look at the biodiversity of the soil. I would see a big difference between industrial farms and organic farms, which had far more species of soil microfauna, microscopic “animals” and nematodes, what I call biodiversity.


Tell me about the work you’re doing now with Innisfree Farm.

Vrain: It’s a small farm, a demonstration garden. My wife is an herbalist, and we grow medicinal plants. Young students come and learn about medicinal plants and organic growing.

It’s my retirement project. I say I’m atoning for my sins.

© Copyright The Organic & Non-GMO Report, June 2013